2,5-Dibromopyridine → 5-Bromo-2-(1-isopropyl-pyrrolidin-3-yloxy)-pyridine

HRID 2421319Notes

Reaction equation

HRID 2421319 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([Br:8])=[CH:4][N:3]=1.[CH:9]([N:12]1[CH2:16][CH2:15][CH:14]([OH:17])[CH2:13]1)([CH3:11])[CH3:10]>>[Br:8][C:5]1[CH:6]=[CH:7][C:2]([O:17][CH:14]2[CH2:15][CH2:16][N:12]([CH:9]([CH3:11])[CH3:10])[CH2:13]2)=[N:3][CH:4]=1

Participants

3

Reactant 2

HCID 693532,5-DibromopyridineHCID 113095221-Isopropyl-3-pyrrolidinol

Product 1

HCID 219142695-Bromo-2-(1-isopropyl-pyrrolidin-3-yloxy)-pyridine

Procedure

Prepared from 2,5-dibromopyridine and 1-isopropylpyrrolidin-3-ol by the method of Example 10 (b).

Sources & evidence

ORD record
ord-49c8cb547ae644568ec81473ad73c28e
Source dataset
uspto-grants-2011_06
Patent number
US07956084B2

Reaction notes

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