HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 21914335, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 4-((5-bromopyridin-2-yl)oxy)piperidine-1-carboxylate | HCID 21914479 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21914335 | HCID 21914335 | — |
Reaction Steps
2-[1-(t-Butyloxycarbonyl)-piperidin-4-yloxy]-5-bromopyridine was stirred in dichloromethane (8 ml). Trifluoroacetic acid (5 ml) was added and stirring continued at room temperature for 1.5 h. Volatile materials were removed in vacuo and the residue was triturated with ether and hexane, then collected by filtration to give the product as a white solid (0.86 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956084B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-158511d06c544a64b4fa39e65e18f8fb |
| Source note | uspto-grants-2011_06 |