2-Bromophenol → HCID 21914428, compound

HRID 2421392Notes

Reaction equation

HRID 2421392 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].CS(O[CH:14]1[CH2:19][CH2:18][N:17]([CH3:20])[CH2:16][CH2:15]1)(=O)=O>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][CH:14]1[CH2:19][CH2:18][N:17]([CH3:20])[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 72442-BromophenolHCID 41906811-Methylpiperidin-4-yl methanesulfonate

Product 1

HCID 21914428HCID 21914428, compound

Procedure

The title compound was prepared from 2-bromophenol and 1-methylpiperidin-4-yl methanesulphonate in a similar manner to Example 134 (b) except that the compound was purified by cation exchange chromatography eluting with ammonia/methanol mixtures.

Workup

  1. customwas purified by cation exchange chromatography
  2. washeluting with ammonia/methanol mixtures

Sources & evidence

ORD record
ord-50eb3bc9abe449c6befcd45222a0f8a1
Source dataset
uspto-grants-2011_06
Patent number
US07956084B2

Reaction notes

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