2,6-Dimethylaniline → HCID 67215468, compound

Participants

Reaction Steps

2,6-dimethylaniline (6.2 g, 51 mmol) was added to a solution of 2-cyanobenzylbromide (10.0 g, 51 mmol) in toluene (250 ml). The solution was heated to reflux for 18 hours. The formed solid was filtered off and washed with toluene (2×25 ml). After drying 11.5 g of the desired compound was obtained as a white solid. The filtrate was heated to reflux for 20 hours. Another 1.5 g of pure product was obtained leading to a total yield of 13.0 g (80%). The product was characterized by

Provenance & Evidence