HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 3-Iodo-8-methyl-quinolin-6-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | N,N,N',N'-Tetramethylethylenediamine | HCID 8037 | — |
| Reactant | 3-Bromo-8-methylquinolin-6-ol | HCID 57417931 | — |
| Catalyst | Copper iodide | HCID 83717 | — |
| Product | 3-Iodo-8-methyl-quinolin-6-ol | HCID 66717817 | — |
Reaction Steps
In a similar procedure to Step 1 of Example 13A, 3-bromo-8-methyl-quinolin-6-ol (preparation described in Example 13 Stage 1) was reacted sodium iodide, copper iodide and N,N,N′,N′-tetramethyl-ethane-1,2-diamine to give the required product, 3-iodo-8-methyl-quinolin-6-ol, as a brown coloured solid (MH+ 286).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956188B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7bedf4af81ef4ff596864e035070ca71 |
| Source note | uspto-grants-2011_06 |