Propylamine → HCID 67214489, compound

Participants

Reaction Steps

Using preparation method 1, 73B (67 mg, 0.3 mmol) was reacted with n-propylamine (27 μL, 19.5 mg, 0.33 mmol). The product was purified by flash chromatography on SiO2 using CH2Cl2/EtOAc 80:20. White crystals were obtained (48 mg, 61%). NMR 1H (ppm, CDCl3): 7.74 (d, J3=8.4 Hz, 2H), 7.53 (d, J3 8.1 Hz, 2H), 7.51 (d, J3=6.4 Hz, 2H), 7.35 (t, J3=7.1 Hz, 2H), 7.27 (tt, J3=7.2 Hz, J4=2.4 Hz, 1H), 7.17 (d, J3=16 Hz, 1H), 7.09 (d, J3=16 Hz, 1H), 6.21 (br. s, 1H), 3.45-3.38 (m, 2H), 1.64 (sext., J3=7.3 Hz, 2H), 0.98 (t, J3=7.4 Hz, 3H).

Provenance & Evidence