Benzylamine → HCID 67213951, compound

Participants

Reaction Steps

Using preparation method 1, 96B (288 mg, 1.5 mmol) was reacted with benzylamine (240 μL, 236 mg, 2.2 mmol). Purification by flash chromatography on SiO2 using CH2Cl2/hexanes 50:50 then CH2Cl2 100% afforded white crystals (316 mg, 74%). NMR 1H (ppm, CDCl3): 7.62 (s, 1H), 7.56-7.53 (m, 1H), 7.36-7.27 (m, 7H), 6.35 (br. s, 1H), 4.64 (d, J3=5.7 Hz, 2H), 2.66-2.60 (m, 2H), 1.64-1.46 (m, 3H), 0.92 (d, J3=6.3 Hz, 6H).

Provenance & Evidence