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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2421687Generated: October 31, 2026

3-Chlorophenethylamine → N-[2-(3-chlorophenyl)ethyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

https://huagongshe.com/reaction/2421687

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-ChlorophenethylamineHCID 139381—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN-[2-(3-chlorophenyl)ethyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamideHCID 11576881—

Reaction Steps

N-[2-(3-chlorophenyl)ethyl]-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.5 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.75 mmol of 2-(3-chlorophenyl)ethylamine. LC/MS [10.47 min; 496 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956191B2
Source datasetuspto-grants-2011_06
ORD IDord-8f8bdd20f2f64df1abdb9ef7df8f2f42
Source noteuspto-grants-2011_06