HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 2-Bromo-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid | HCID 57649649 | — |
| Product | 2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide | HCID 11612686 | — |
Reaction Steps
2-Bromo-5-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethyl)-isonicotinamide was synthesized according to General Method 3, starting with 145 mg (0.33 mmol) of 2-bromo-5-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid 51 mg (0.83 mmol) of 2-amino-ethanol. LC/MS: [8.98 min, 480, 482]
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07956191B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7af465b502a84a4ca720955fc1761d6d |
| Source note | uspto-grants-2011_06 |