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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2421734Generated: October 27, 2026

O-Benzylhydroxylamine → N-(benzyloxy)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

https://huagongshe.com/reaction/2421734

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-BenzylhydroxylamineHCID 102313—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN-(benzyloxy)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamideHCID 11503610—

Reaction Steps

N-(benzyloxy)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.5 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.72 mmol of O-benzyl-hydroxylamine. LC/MS [9.50 min; 464 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956191B2
Source datasetuspto-grants-2011_06
ORD IDord-c877bf7405824716a2d3300b933c9f3a
Source noteuspto-grants-2011_06