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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2421736Generated: October 27, 2026

2,4-Difluorobenzylamine → N-(2,4-difluorobenzyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide

https://huagongshe.com/reaction/2421736

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reactant3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
ProductN-(2,4-difluorobenzyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamideHCID 11554824—

Reaction Steps

N-(2,4-difluorobenzyl)-3-[(2-fluoro-4-iodophenyl)amino]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.33 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.49 mmol of 2,4-difluorobenzylamine. LC/MS [6.28 min; 484 (M+1)]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07956191B2
Source datasetuspto-grants-2011_06
ORD IDord-b4bcc832ab8b4a7c8185fb606d3df6cf
Source noteuspto-grants-2011_06