HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86629178, compound → HCID 86629177, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86629178 | HCID 86629178 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86629177 | HCID 86629177 | 91.5% |
Reaction Steps
410 mg of 43 (0.925 mmol), 41 mg of Pd/C (10%) and 20 mL of MeOH are hydrogenated at 7 bar for 10 hours at 20° C. in an autoclave. After filtering off the catalyst through Celite, the solvent is evaporated off to give 350 mg of expected product 44, which product is used directly in the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960373B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-80097046ef2749a59f4455ddc2e8ab86 |
| Source note | uspto-grants-2011_06 |