HCID 86629184, compound → HCID 86629183, compound

Participants

Reaction Steps

2.43 g of 53 (6.53 mmol), 285 mg of Pd/C (10%) and 174 mL of methanol are hydrogenated at 5 bar for 10 hours at 20° C. in an autoclave. After filtering off the catalyst through Celite, the solvent is evaporated off and 1.8 g of expected product 54 are obtained (brown oil), which product is used directly in the following step.

Provenance & Evidence