Potassium Carbonate → HCID 67242711, compound

Participants

Reaction Conditions

Reaction Steps

5-Amino-1-ethyl-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (0.6 g, 3.3 mmol, see Preparation 5), benzyl bromoacetate (1.6 ml, 4.8 mmol), and potassium carbonate (0.5 g, 3.3 mmol) were suspended in dimethylformamide (30 ml) and heated overnight at 50° C. The solvent was evaporated under reduced pressure and the residue was passed through a silica-gel column, eluting with hexane/ethyl acetate 3:2, to yield 1.0 g of the desired final product. Yield=92%

Provenance & Evidence