HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → HCID 58834850, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | 2-Fluoro-5-(trifluoromethyl)phenyl isocyanate | HCID 2733380 | — |
| Reactant | HCID 11826263 | HCID 11826263 | — |
| Product | HCID 58834850 | HCID 58834850 | — |
Reaction Steps
Starting with 150 mg (0.34 mmol) of the iminophosphorane from Example 3A, 74 mg (0.34 mmol) of 2-fluoro-5-(trifluoromethyl)phenyl isocyanate and 61 mg (0.34 mmol) of N-(4-fluorophenyl)piperazine, the general procedure [E] and chromatographic purification (method 2) give 34 mg (17% of theory) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960387B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-f206db4d417b4e84a9158e54e69b71f9 |
| Source note | uspto-grants-2011_06 |