HCID 67242139, compound → HCID 67242785, compound

HRID 2422135Notes

Reaction equation

HRID 2422135 reaction equation
[C:1]([N:5]1[C:9](=[O:10])[C:8](Cl)=[C:7]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[S:6]1(=[O:19])=[O:18])([CH3:4])([CH3:3])[CH3:2].Cl.[NH2:21][CH2:22][CH2:23][C:24]([O:26][CH:27]1[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29][CH2:28]1)=[O:25]>>[C:1]([N:5]1[C:9](=[O:10])[C:8]([NH:21][CH2:22][CH2:23][C:24]([O:26][CH:27]2[CH2:28][CH2:29][N:30]([CH3:33])[CH2:31][CH2:32]2)=[O:25])=[C:7]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[S:6]1(=[O:19])=[O:18])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 67242139HCID 67242139, compoundHCID 672426272-tert-Butyl-4-chloro-5-phenylisothiazol-3(2H)-one 1,1-dioxide

Product 1

HCID 67242785HCID 67242785, compound

Procedure

The title compound was prepared from 2-tert-butyl-4-chloro-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 1-methylpiperidin-4-yl β-alaninate hydrochloride in a similar manner as described for Example 164. Mass Spectrum: [M+H]+ 450.12, [M−H]− 448.23.

Sources & evidence

ORD record
ord-f49232067db44555a937fa5c44c662c0
Source dataset
uspto-grants-2011_06
Patent number
US07960380B2

Reaction notes

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