HCID 67146660, compound → HCID 85970834, compound

Participants

Reaction Steps

To a solution of 4-[[methyl(4-phenyl-2-thiazolyl)amino]methyl]benzenemethanol (1.0 g, 3.2 mmol) in ethyl acetate (40 mL) was added manganese dioxide (4.0 g), and the mixture was stirred at room temperature for 3 hrs. Insoluble material was filtered off, and the filtrate was concentrated. The residue was purified by silica gel column chromatography (hexane/ethyl acetate=5:1) to give the title compound (0.80 g, yield 81%). oil.

Provenance & Evidence