Hydrochloric Acid → HCID 57541968, compound

Participants

Reaction Steps

A solution of methyl 4-[(3′-formyl-[1,1′-biphenyl]-3-yl) methoxy]benzenepropanoate (0.80 g, 2.1 mmol) in methanol (5 mL) and tetrahydrofuran (2 mL) was ice-cooled, and sodium borohydride (81 mg, 2.1 mmol) was added. The mixture was stirred under ice-cooling for 30 min. The reaction mixture was added to 0.2N hydrochloric acid (11 mL), and the mixture was extracted with ethyl acetate. The extract was washed with water and concentrated under reduced pressure to give the title compound 0.80 g (quantitative). oil.

Provenance & Evidence