Sodium Hydroxide → HCID 57541919, compound

Participants

Reaction Steps

A mixture of methyl 3-[4-[[3-(2,6-dimethylbenzyl)benzyl]oxy]phenyl]propanoate (125 mg), 2N aqueous sodium hydroxide solution (3 mL) and ethanol (10 mL) was stirred at room temperature for 1 hr. The reaction mixture was concentrated and added to a mixture of 1N hydrochloric acid aqueous solution (10 mL) and water (30 mL). The precipitated solid was collected by filtration, washed with water and hexane and dried to give the title compound (99 mg, yield 82%) as colorless crystals.

Provenance & Evidence