HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxybenzotriazole, ammonium salt → 3-(4-((2'-(Aminocarbonyl)biphenyl-3-yl)methoxy)phenyl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxybenzotriazole, ammonium salt | HCID 22033809 | — |
| Reactant | 3'-[4-(2-Tert-butoxycarbonylethyl)phenoxymethyl]biphenyl-2-carboxylic acid | HCID 57541846 | — |
| Product | 3-(4-((2'-(Aminocarbonyl)biphenyl-3-yl)methoxy)phenyl)propanoic acid | HCID 23082981 | — |
Reaction Steps
The title compound was synthesized in the same manner as in Example 285 from 3′-[4-(2-tert-butoxycarbonylethyl)phenoxymethyl]biphenyl-2-carboxylic acid and 1-hydroxybenzotriazole ammonium salt. colorless crystals (yield 66%). MS (APCI−): 374 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960369B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-7cbd2a406f344ab38e2a83c68be1da89 |
| Source note | uspto-grants-2011_06 |