Benzenepropanoic acid, 4-hydroxy-, methyl ester → HCID 23082853, compound

HRID 2422304Notes

Reaction equation

HRID 2422304 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][CH:3]=1.[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=1[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH2:28]O)[CH:23]=1>>[F:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([F:21])[C:16]=1[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH2:28][O:1][C:2]2[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11])=[CH:6][CH:7]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 79706Benzenepropanoic acid, 4-hydroxy-, methyl esterHCID 23082779(2',6'-Difluoro[1,1'-biphenyl]-3-yl)methanol

Product 1

HCID 23082853HCID 23082853, compound

Procedure

The title compound was synthesized in the same manner as in Example 277 from methyl 3-(4-hydroxyphenyl)propanoate and (2′,6′-difluorobiphenyl-3-yl)methanol. colorless oil (yield 60%).

Sources & evidence

ORD record
ord-b84adfa86a71477abefe75a68d9f18f7
Source dataset
uspto-grants-2011_06
Patent number
US07960369B2

Reaction notes

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