Ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoate → HCID 23083042, compound

HRID 2422305Notes

Reaction equation

HRID 2422305 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12].[CH2:16]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH2:24][CH3:25])[C:19]=1[C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH2:32]O)[CH:27]=1)[CH3:17]>>[CH2:16]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH2:24][CH3:25])[C:19]=1[C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH2:32][O:8][C:6]2[CH:5]=[CH:4][C:3]([CH2:9][CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[C:2]([F:1])[CH:7]=2)[CH:27]=1)[CH3:17]

Participants

3

Reactant 2

HCID 23082888Ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoateHCID 23083167HCID 23083167, compound

Product 1

HCID 23083042HCID 23083042, compoundYield 80%

Procedure

The title compound was synthesized in the same manner as in Example 277 from ethyl 3-(2-fluoro-4-hydroxyphenyl)propanoate and (2′,6′-diethylbiphenyl-3-yl)methanol. a yellow oily substance (yield 80%).

Sources & evidence

ORD record
ord-e2664efb35c54ec5ba6092a1cde66518
Source dataset
uspto-grants-2011_06
Patent number
US07960369B2

Reaction notes

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