4-Fluorophenylboronic acid → HCID 25056887, compound

Participants

Reaction Steps

7-(Azidomethyl)-4-(4-fluorophenyl)-2H-chromen-2-one was prepared using the general procedure described in example 1, steps 3-7, but substituting 4-fluorobenzeneboronic acid in place of 3-fluorobenzeneboronic acid. The title compound was prepared using 1,1-dicyclopropylprop-2-yn-1-ol and 7-(azidomethyl)-4-(4-fluorophenyl)-2H-chromen-2-one using the general cycloaddition procedure described in example 12. 1H NMR (400 MHz, acetone-d6): 1H NMR (400 MHz, acetone-d6): 7.95 (s, 1H), 7.7-7.65 (m, 1H), 7.52 (d, 1H), 7.40-7.35 (m, 3H), 7.30 (d, 1H), 6.40 (s, 1H), 5.80 (s, 2H), 3.72 (s, 1H), 1.45-1.35 (m, 2H), 0.55-0.45 (m, 4H), 0.45-0.35 (m, 2H), 0.30-0.20 (m, 2H).

Provenance & Evidence