HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 6-Chloro-2-{4-[(1-cyclobutylpiperidin-4-yl)oxy]-2-methoxyphenyl}-3-methylpyrido[3,4-d]pyrimidin-4(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 5-Amino-2-chloro-isonicotinic acid | HCID 22736791 | — |
| Reactant | 4-[(1-Cyclobutylpiperidin-4-yl)oxy]-2-methoxybenzaldehyde | HCID 86624462 | — |
| Product | 6-Chloro-2-{4-[(1-cyclobutylpiperidin-4-yl)oxy]-2-methoxyphenyl}-3-methylpyrido[3,4-d]pyrimidin-4(3H)-one | HCID 11496208 | — |
Reaction Steps
The entitled compound was obtained according to the method of Example 15 but starting from 5-amino-2-chloroisonicotinic acid, methylamine and 4-[(1-cyclobutylpiperidin-4-yl)oxy]-2-methoxybenzaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960394B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-cf6393c9689843d89ea7ca1dcf44f718 |
| Source note | uspto-grants-2011_06 |