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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2422616Generated: October 26, 2026

Methylamine → 2-{4-[(1-Cyclobutylpiperidin-4-yl)oxy]phenyl}-5-fluoro-3-methylquinazolin-4(3H)-one

https://huagongshe.com/reaction/2422616

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant2-Amino-6-fluorobenzoic acidHCID 521142—
Reactant4-[(1-Cyclobutylpiperidin-4-yl)oxy]-2-methoxybenzaldehydeHCID 86624462—
Product2-{4-[(1-Cyclobutylpiperidin-4-yl)oxy]phenyl}-5-fluoro-3-methylquinazolin-4(3H)-oneHCID 11509730—

Reaction Steps

The entitled compound was obtained according to the method of Example 15 but starting from 2-amino-6-fluorobenzoic acid, methylamine and 4-[(1-cyclobutylpiperidin-4-yl)oxy]-2-methoxybenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960394B2
Source datasetuspto-grants-2011_06
ORD IDord-8a3a7d7c69bd416dbe6b7552e1b8b21c
Source noteuspto-grants-2011_06