Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → 3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | 3-Aminopicolinic acid | HCID 73836 | — |
| 반응물 | 4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde | HCID 7379340 | — |
| 생성물 | 3-Methyl-2-(4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}phenyl)pyrido[3,2-d]pyrimidin-4(3H)-one | HCID 11494881 | — |
반응 단계
The entitled compound was obtained according to the method of Example 15 but starting from 3-aminopyridin-2-carboxylic acid, methylamine and 4-{3-[(3S)-3-methylpiperidin-1-yl]propoxy}benzaldehyde. The resulting compound was recrystallized from diethyl ether-heptane to give a colorless acicular crystal (m.p. 83.5-88.5° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07960394B2 |
| 출처 데이터셋 | uspto-grants-2011_06 |
| ORD ID | ord-26b370b5224e4669b1e0f2ab18ea402c |
| 출처 메모 | uspto-grants-2011_06 |