Acetonitrile → HCID 67183004, compound

HRID 2422707Notes

Reaction equation

HRID 2422707 reaction equation
CC(C)([O-])C.[K+].[C:7](#[N:9])[CH3:8].[CH3:10][S:11][C:12]1[CH:19]=[CH:18][C:15]([C:16]#[N:17])=[CH:14][CH:13]=1>>[NH2:17][C:16]([C:15]1[CH:18]=[CH:19][C:12]([S:11][CH3:10])=[CH:13][CH:14]=1)=[CH:8][C:7]#[N:9]

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 5909604-(Methylthio)benzonitrileHCID 23665647Potassium tert-butoxide

Product 1

HCID 67183004HCID 67183004, compound

Procedure

Using a similar procedure to that of Preparation IX-2, but using 1.5 equivalents of potassium t-butoxide and 1.5 equivalents of acetonitrile per 1 equivalent of 4-(methylthio) benzonitrile, there is obtained 3-amino-3-[4-(methylthio)phenyl]acrylonitrile.

Workup

  1. customof Preparation IX-2

Sources & evidence

ORD record
ord-e721ad9f821643e9a3a5b0417d69828f
Source dataset
uspto-grants-2011_06
Patent number
US07960419B2

Reaction notes

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