HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzimidazole → N-[2-Methyl-3-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzimidazole | HCID 78572 | — |
| Reactant | Trifluoromethyl toluidine | HCID 2735932 | — |
| Product | N-[2-Methyl-3-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine | HCID 15602782 | — |
Reaction Steps
The title compound was prepared from 2-chlorobenzimidazole and 2-methyl-3-(trifluoromethyl)aniline by Procedure A. The product was isolated by filtration and preparative LCMS to give the title compound as the free base (white solid, mp 204-206° C.). MS(ES+) m/z 292 ([M+1]+, 100).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960561B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-c2ecd0153b1f45829e11508787317341 |
| Source note | uspto-grants-2011_06 |