HCID 67240989, compound → HCID 67241531, compound

Participants

Reaction Steps

Pd/C 10 wt. % (250 mg, 0.236 mmol was added to a solution of N-benzenesulfonyl-5-benzyloxy-6-fluoroindole (Intermediate 27, 250 mg, 6.55 mmol) in ethanol (100 mL). The reaction mixture was stirred under an atmosphere of hydrogen (1 atm) at room temperature for 2 hours, filtered and evaporated. The crude material was purified by flash chromatography on silica gel using 0.5% MeOH/DCM as the eluent to give the title compound (1.79 g) as a white solid. MS m/z 292 [M+H]+.

Provenance & Evidence