HCID 59864862, compound → HCID 59864837, compound

HRID 2423292Notes

Reaction equation

HRID 2423292 reaction equation
[CH3:1][O:2][C:3]1[CH:32]=[C:31]([CH2:33][C:34]([O:36][CH3:37])=[O:35])[CH:30]=[CH:29][C:4]=1[O:5][C:6]1[C:7]([N+:26]([O-])=O)=[C:8]2[C:12](=[CH:13][CH:14]=1)[N:11](C(OC(C)(C)C)=O)[C:10]([C:22]([F:25])([F:24])[F:23])=[CH:9]2>CO.[Pd]>[NH2:26][C:7]1[C:6]([O:5][C:4]2[CH:29]=[CH:30][C:31]([CH2:33][C:34]([O:36][CH3:37])=[O:35])=[CH:32][C:3]=2[O:2][CH3:1])=[CH:14][CH:13]=[C:12]2[C:8]=1[CH:9]=[C:10]([C:22]([F:25])([F:23])[F:24])[NH:11]2

Participants

4

Reactant 1

HCID 59864862HCID 59864862, compound

Product 1

HCID 59864837HCID 59864837, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of 14.4 (0.020 g, 0.047 mmol) in methanol (2 mL), was added 10% Pd/C (0.006 g, 0.005 mmol). The mixture was stirred under hydrogen at room temperature for 1 h. Solvent was removed after filtration to give a residue. MS ESI (pos.) m/z: 395.1 (M+H)+.

Workup

  1. customSolvent was removed
  2. filtrationafter filtration
  3. customto give a residue

Sources & evidence

ORD record
ord-b428e6d2a8cb445089d057c70c40aad0
Source dataset
uspto-grants-2011_06
Patent number
US07960567B2

Reaction notes

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