Chlorotrimethylsilane → HCID 59864851, compound

HRID 2423295Notes

Reaction equation

HRID 2423295 reaction equation
[C:1]([CH2:4][C:5]1[CH:26]=[CH:25][C:8]([O:9][C:10]2[C:11]([N+:22]([O-:24])=[O:23])=[C:12]3[C:16](=[CH:17][CH:18]=2)[NH:15][C:14]([C:19]([OH:21])=[O:20])=[CH:13]3)=[C:7]([O:27][CH3:28])[CH:6]=1)([OH:3])=[O:2].[CH3:29][Si](Cl)(C)C>CO>[CH3:28][O:27][C:7]1[CH:6]=[C:5]([CH2:4][C:1]([O:3][CH3:29])=[O:2])[CH:26]=[CH:25][C:8]=1[O:9][C:10]1[C:11]([N+:22]([O-:24])=[O:23])=[C:12]2[C:16](=[CH:17][CH:18]=1)[NH:15][C:14]([C:19]([OH:21])=[O:20])=[CH:13]2

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 59864850HCID 59864850, compound

Product 1

HCID 59864851HCID 59864851, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 15.4 (0.37 g, 0.96 mmol) in CH3OH (10 mL), was added TMSCl (0.1 g, 0.92 mmol). The mixture was stirred at room temperature for 3 h. Solvent was removed to give a residue, which was used without further purification. MS ESI (pos.) m/z: 401.0 (M+H)+.

Workup

  1. customSolvent was removed
  2. customto give a residue, which
  3. customwas used without further purification

Sources & evidence

ORD record
ord-a325d09c38b74bc3a04391dc5208d636
Source dataset
uspto-grants-2011_06
Patent number
US07960567B2

Reaction notes

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