Citronellal → (-)-Menthol

Participants

Reaction Conditions

Reaction Steps

Example 1 was repeated using L-isopulegol with a purity of 97.1% and 84% ee, which was introduced at a rate of 24.5 g/h (total amount 466 g) into the reactor at a hydrogen pressure of 40 bar. The main reactor (MR) was heated to 80° C., the postreactor to 70° C. The L-isopulegol used had the following composition: L-isopulegol: 97.1 GC % by weight, citronellol: 0.05 GC % by weight, citronellal: 0.40 GC % by weight, isopulegol isomer: 0.45 GC % by weight, secondary components: 0.34 GC % by weight. L-menthol (84% ee) was obtained in an amount of 468 g, corresponding to a rate of 24.6 g/h. The chemical purity of the L-menthol output is shown in Table 3.

Provenance & Evidence