HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(4-bromobutoxy)benzoate → 4-{4-[1-(2,2-Dimethyl-propyl)-4-propyl-1h-indol-5-yloxy]-butoxy}-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(4-bromobutoxy)benzoate | HCID 10979046 | — |
| Reactant | 5-hydroxy-4-propyl-N-neopentylindole | HCID 18672475 | — |
| Product | 4-{4-[1-(2,2-Dimethyl-propyl)-4-propyl-1h-indol-5-yloxy]-butoxy}-benzoic acid | HCID 11952345 | — |
Reaction Steps
Similar procedures as outlined in examples 1 & 26 were followed using methyl 4-(4-bromobutoxy)benzoate and 1-(2,2-dimethylpropyl)-4-propyl-1H-indol-5-ol. 1H NMR (500 MHz, DMSO) δ 12.64 (s, 1H), 7.92 (d, 2H), 7.24 (d, 1H), 7.20 (s, 1H), 7.02 (d, 2H), 6.87 (d, 1H), 6.37 (d, 1H), 4.14 (t, 2H), 4.01 (t, 2H), 3.90 (s, 2H), 2.77 (t, 2H), 1.95 (m, 2H), 1.88 (m, 2H), 1.59 (m, 2H), 0.92 (s, 9H), 0.90 (t, 3H). MS (ESI): 438 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960417B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-3efbe1afa27d41c782acecd46f1e8f20 |
| Source note | uspto-grants-2011_06 |