HCID 23087111, compound → HCID 57934423, compound

HRID 2423569Notes

Reaction equation

HRID 2423569 reaction equation
NC1(C[O:8]C2C=CC(C#N)=CC=2)CCCC1.[C:17]([C:19]1[CH:39]=[CH:38][C:22]([O:23][CH2:24][C:25]2([NH:30][C:31](=[O:37])[O:32][C:33]([CH3:36])([CH3:35])[CH3:34])[CH2:29][CH2:28][CH2:27][CH2:26]2)=[CH:21][CH:20]=1)#N>>[CH:17]([C:19]1[CH:39]=[CH:38][C:22]([O:23][CH2:24][C:25]2([NH:30][C:31](=[O:37])[O:32][C:33]([CH3:36])([CH3:35])[CH3:34])[CH2:29][CH2:28][CH2:27][CH2:26]2)=[CH:21][CH:20]=1)=[O:8]

Participants

3

Reactant 2

HCID 23087111HCID 23087111, compoundHCID 86605236HCID 86605236, compound

Product 1

HCID 57934423HCID 57934423, compound

Procedure

Synthesized from 4-(1-aminocyclopentylmethoxy)benzonitrile according to an analogous synthetic method to Preparation Example 19, tert-butyl [1-(4-cyanophenoxymethyl)cyclopentyl]carbamate (1.0 g) was used according to an analogous synthetic method to Preparation Example 20 to provide the title compound (688 mg).

Workup

  1. customwas used according to an analogous synthetic method to Preparation Example 20

Sources & evidence

ORD record
ord-113e1e8886ba455cbf696d662000fc1c
Source dataset
uspto-grants-2011_06
Patent number
US07960412B2

Reaction notes

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