HRID2423599

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23087211

未命名化合物

HCID23087266

未命名化合物

PRODUCTS

产物

HCID57933806

未命名化合物

PROCEDURE

实验过程

Synthesized from [4-(2-diisopropylaminoethoxy)phenyl][5-methoxy-2-(6-methoxynaphthalen-2-yl)phenyl]methanone according to an analogous synthetic method to Example 337 described below, diisopropyl{2-{4-[5-methoxy-2-(6-methoxynaphthalen-2-yl)benzyl]phenoxy}ethyl}amine (398 mg) was used according to an analogous synthetic method to Example 111 described below to provide the title compound (80 mg).

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-acc5b19e52dc489da970c0d6a4c3ad93
来源数据集: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US07960412B2
来源说明: uspto-grants-2011_06

反应SMILES

[CH:1]([N:4]([CH:36]([CH3:38])[CH3:37])[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]([C:16]2[CH:21]=[C:20]([O:22]C)[CH:19]=[CH:18][C:17]=2[C:24]2[CH:33]=[CH:32][C:31]3[C:26](=[CH:27][CH:28]=[C:29]([O:34]C)[CH:30]=3)[CH:25]=2)=O)=[CH:10][CH:9]=1)([CH3:3])[CH3:2].C(N(C(C)C)CCOC1C=CC(CC2C=C(OC)C=CC=2C2C=CC3C(=CC=C(OC)C=3)C=2)=CC=1)(C)C>>[CH:36]([N:4]([CH:1]([CH3:3])[CH3:2])[CH2:5][CH2:6][O:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][C:16]2[CH:21]=[C:20]([OH:22])[CH:19]=[CH:18][C:17]=2[C:24]2[CH:25]=[C:26]3[C:31](=[CH:32][CH:33]=2)[CH:30]=[C:29]([OH:34])[CH:28]=[CH:27]3)=[CH:10][CH:9]=1)([CH3:37])[CH3:38]