HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-4-fluoro-2-nitrobenzene → HCID 23087411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-4-fluoro-2-nitrobenzene | HCID 2773383 | — |
| Reactant | 6-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate | HCID 15330256 | — |
| Reactant | Tributyl(4-fluoro-2-nitrophenyl)tin | HCID 23087155 | — |
| Product | HCID 23087411 | HCID 23087411 | — |
Reaction Steps
Synthesized from 1-bromo-4-fluoro-2-nitrobenzene according to an analogous synthetic method to Preparation Example 76, tributyl(4-fluoro-2-nitrophenyl)tin (7.1 g) and 6-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (2.2 g) were used according to an analogous synthetic method to Preparation Example 77 to provide 3-(4-fluoro-2-nitrophenyl)-7-methoxy-1,2-dihydronaphthalene (1.4 g). The total amount of this compound was used according to an analogous synthetic method to Example 30 to provide the title compound (1.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-df1c56a679074deba863db19228d68f9 |
| Source note | uspto-grants-2011_06 |