Ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine → HCID 57933818, compound

HRID 2423631Notes

Reaction equation

HRID 2423631 reaction equation
C(NC1C=C(OC)C=CC=1C1CCC2C(=CC=C(OC)C=2)C1)C.[CH2:24]([N:26]([CH2:47][CH3:48])[C:27]1[CH:32]=[C:31]([O:33]C)[CH:30]=[CH:29][C:28]=1[CH:35]1[CH2:44][CH2:43][C:42]2[C:37](=[CH:38][CH:39]=[C:40]([O:45]C)[CH:41]=2)[CH2:36]1)[CH3:25]>>[CH2:47]([N:26]([CH2:24][CH3:25])[C:27]1[CH:32]=[C:31]([OH:33])[CH:30]=[CH:29][C:28]=1[CH:35]1[CH2:44][CH2:43][C:42]2[CH:41]=[C:40]([OH:45])[CH:39]=[CH:38][C:37]=2[CH2:36]1)[CH3:48]

Participants

3

Reactant 2

HCID 23087318Ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amineHCID 23087350HCID 23087350, compound

Product 1

HCID 57933818HCID 57933818, compoundYield 79.5%

Procedure

Synthesized from ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine according to an analogous synthetic method to Example 36, diethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (288 mg) was used according to an analogous synthetic method to Example 111 described below to proide the title compound (210 mg).

Sources & evidence

ORD record
ord-63933b1924dd4210aab3e93dca61e594
Source dataset
uspto-grants-2011_06
Patent number
US07960412B2

Reaction notes

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