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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2423633Generated: October 30, 2026

N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]benzamide → 6-[2-(Benzylethylamino)-4-hydroxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol

https://huagongshe.com/reaction/2423633

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]benzamideHCID 57934332—
ReactantBenzylethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amineHCID 66627069—
Product6-[2-(Benzylethylamino)-4-hydroxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-olHCID 6662763864.1%

Reaction Steps

Synthesized from N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]benzamide according to an analogous synthetic method to Example 337 described below, benzylethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (151 mg) was used according to an analogous synthetic method to Example 111 described below to provide the title compound (90 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07960412B2
Source datasetuspto-grants-2011_06
ORD IDord-eb5d518af25d4441bb6125d51e091dc2
Source noteuspto-grants-2011_06