HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-piperidin-1-ylacetamide → 6-{2-[Ethyl(2-piperidin-1-ylethyl)amino]-4-hydroxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-piperidin-1-ylacetamide | HCID 57933990 | — |
| Reactant | Ethyl [5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl](2-piperidin-1-ylethyl)amine | HCID 66627658 | — |
| Product | 6-{2-[Ethyl(2-piperidin-1-ylethyl)amino]-4-hydroxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 57934100 | — |
Reaction Steps
Synthesized from N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]-2-piperidin-1-ylacetamide according to an analogous synthetic method to Example 337 described below, the total amount of ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl](2-piperidin-1-ylethyl)amine (108 mg) was used according to an analogous synthetic method to Example 111 described below to provide the title compound (84 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-45f06f9484dd4e6f8874efe51afa6a18 |
| Source note | uspto-grants-2011_06 |