HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Piperidin-1-ylethoxy)benzoyl chloride hydrochloride → [5-Methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl][4-(2-piperidin-1-ylethoxy)benzyl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Piperidin-1-ylethoxy)benzoyl chloride hydrochloride | HCID 16111922 | — |
| Reactant | 5-Methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine | HCID 23087205 | — |
| Product | [5-Methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl][4-(2-piperidin-1-ylethoxy)benzyl]amine | HCID 57934017 | 65.3% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine (312 mg) and 4-(2-piperidin-1-ylethoxy)benzoyl chloride hydrochloride (1.0 g) according to an analogous synthetic method to Example 110, the title compound (360 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-ca9cfb5e76a843c99d11ebcb0a19bd2c |
| Source note | uspto-grants-2011_06 |