HRID2423723

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23087205

未命名化合物

HCID66625687

未命名化合物

PRODUCTS

生成物

结构：COc1ccc2c(c1)CCC(c1ccc(OC)cc1NCc1ccc(OCCN(C(C)C)C(C)C)cc1)C2

HCID23087201

未命名化合物

收率 96.5%

PROCEDURE

实验过程

Synthesized from 4-(2-diisopropylaminoethoxy)benzoic acid hydrochloride (240 mg) and 5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenylamine (150 mg) according to an analogous synthetic method to Example 152, the title compound (264 mg) was obtained.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-66a49db0677b4c40a696e445bfe72c78
来源数据集: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07960412B2
来源说明: uspto-grants-2011_06

反应 SMILES

Cl.[CH:2]([N:5]([CH:18]([CH3:20])[CH3:19])[CH2:6][CH2:7][O:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=O)=[CH:11][CH:10]=1)([CH3:4])[CH3:3].[CH3:21][O:22][C:23]1[CH:24]=[CH:25][C:26]([CH:30]2[CH2:39][CH2:38][C:37]3[C:32](=[CH:33][CH:34]=[C:35]([O:40][CH3:41])[CH:36]=3)[CH2:31]2)=[C:27]([NH2:29])[CH:28]=1>>[CH:2]([N:5]([CH:18]([CH3:20])[CH3:19])[CH2:6][CH2:7][O:8][C:9]1[CH:17]=[CH:16][C:12]([CH2:13][NH:29][C:27]2[CH:28]=[C:23]([O:22][CH3:21])[CH:24]=[CH:25][C:26]=2[CH:30]2[CH2:39][CH2:38][C:37]3[C:32](=[CH:33][CH:34]=[C:35]([O:40][CH3:41])[CH:36]=3)[CH2:31]2)=[CH:11][CH:10]=1)([CH3:4])[CH3:3]