HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23087237, compound → HCID 57934247, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23087237 | HCID 23087237 | — |
| Reactant | 3-Fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride | HCID 66626827 | — |
| Reactant | HCID 66627486 | HCID 66627486 | — |
| Product | HCID 57934247 | HCID 57934247 | 20.1% |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxy-1-methyl-1H-indol-2-yl)phenylamine (500 mg) and 3-fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride (920 mg) according to an analogous synthetic method to Example 114, [3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxy-1-methyl-1H-indol-2-yl)phenyl]amine (210 mg) was used according to an analogous synthetic method to Example 364 described below to provide the title compound (40 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-524b313d6b8a45a484365e03c0cb5eba |
| Source note | uspto-grants-2011_06 |