HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23087164, compound → HCID 23087081, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23087164 | HCID 23087164 | — |
| Reactant | HCID 23087329 | HCID 23087329 | — |
| Reactant | 3-Fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride | HCID 66626827 | — |
| Product | HCID 23087081 | HCID 23087081 | — |
Reaction Steps
Synthesized from 5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenylamine and 3-fluoro-4-(2-piperidin-1-ylethoxy)benzoic acid hydrochloride according to an analogous synthetic method to Example 114, [3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenyl]amine (231 mg) was used according to an analogous synthetic method to Example 36 to provide ethyl[3-fluoro-4-(2-piperidin-1-ylethoxy)benzyl][5-methoxy-2-(6-methoxybenzo[b]thiophen-2-yl)phenyl]amine (195 mg). The total amount of this compound was used according to an analogous synthetic method to Example 111 to provide the title compound (170 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-3a6f34c8feff4a79bbb5433ea1a20d58 |
| Source note | uspto-grants-2011_06 |