Piperidine, 1-(2-chloroethyl)-, hydrochloride → 6-{4-Hydroxy-2-{2-[4-(2-piperidin-1-ylethoxy)phenyl]ethyl}phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol

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Reaction Steps

Synthesized from 4-{2-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]ethyl}phenol and 1-(2-chloroethyl)piperidine hydrochloride according to an analogous synthetic method to Preparation Example 40, 1-{2-{4-{2-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]ethyl}phenoxy}ethyl}piperidine (167 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (116 mg).

Provenance & Evidence