HRID2423898

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCN(CC)CCOc1ccc(CN(CC)c2cc(OC)ccc2C2CCc3cc(OC)ccc3C2)cc1

HCID23087137

未命名化合物

结构：CCN(CC)CCOc1ccc(C(=O)N(CC)c2cc(OC)ccc2C2CCc3cc(OC)ccc3C2)cc1

HCID57934350

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCOc1ccc(CCCNc2cc(O)ccc2C2CCc3cc(O)ccc3C2)cc1

HCID66625768

未命名化合物

PROCEDURE

实验过程

Synthesized from 4-(2-diethylaminoethoxy)-N-ethyl-N-[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]benzamide according to an analogous synthetic method to Example 337, [4-(2-diethylaminoethoxy)benzyl]ethyl[5-methoxy-2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (149 mg) was used according to an analogous synthetic method to Example 111 to provide the title compound (159 mg).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fb2e3b10bb1b4bf09c14a45c3032823a
来源数据集: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07960412B2
来源说明: uspto-grants-2011_06

反应 SMILES

C(N(CC)CCOC1C=CC(C([N:13]([CH2:34][CH3:35])[C:14]2[CH:19]=[C:18]([O:20]C)[CH:17]=[CH:16][C:15]=2[CH:22]2[CH2:31][CH2:30][C:29]3[C:24](=[CH:25][CH:26]=[C:27]([O:32]C)[CH:28]=3)[CH2:23]2)=O)=CC=1)C.[CH2:40]([N:42]([CH2:76][CH3:77])[CH2:43][CH2:44][O:45][C:46]1[CH:75]=[CH:74][C:49]([CH2:50]N(CC)C2C=C(OC)C=CC=2C2CCC3C(=CC=C(OC)C=3)C2)=[CH:48][CH:47]=1)[CH3:41]>>[CH2:76]([N:42]([CH2:40][CH3:41])[CH2:43][CH2:44][O:45][C:46]1[CH:47]=[CH:48][C:49]([CH2:50][CH2:35][CH2:34][NH:13][C:14]2[CH:19]=[C:18]([OH:20])[CH:17]=[CH:16][C:15]=2[CH:22]2[CH2:31][CH2:30][C:29]3[CH:28]=[C:27]([OH:32])[CH:26]=[CH:25][C:24]=3[CH2:23]2)=[CH:74][CH:75]=1)[CH3:77]