[2-(4-Benzyloxyphenyl)ethyl]ethyl[2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine → HCID 23087457, compound

HRID 2423917Notes

Reaction equation

HRID 2423917 reaction equation
C(OC1C=CC(CCNC2C=CC=CC=2C2CCC3C(=CC=C(OC)C=3)C2)=CC=1)C1C=CC=CC=1.C([O:43][C:44]1[CH:49]=[CH:48][C:47]([CH2:50][CH2:51][N:52]([CH2:71][CH3:72])[C:53]2[CH:58]=[CH:57][CH:56]=[CH:55][C:54]=2[CH:59]2[CH2:68][CH2:67][C:66]3[C:61](=[CH:62][CH:63]=[C:64]([O:69][CH3:70])[CH:65]=3)[CH2:60]2)=[CH:46][CH:45]=1)C1C=CC=CC=1>>[CH2:71]([N:52]([C:53]1[CH:58]=[CH:57][CH:56]=[CH:55][C:54]=1[CH:59]1[CH2:68][CH2:67][C:66]2[C:61](=[CH:62][CH:63]=[C:64]([O:69][CH3:70])[CH:65]=2)[CH2:60]1)[CH2:51][CH2:50][C:47]1[CH:48]=[CH:49][C:44]([OH:43])=[CH:45][CH:46]=1)[CH3:72]

Participants

3

Reactant 2

HCID 23087077[2-(4-Benzyloxyphenyl)ethyl]ethyl[2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amineHCID 23087336[2-(4-Benzyloxyphenyl)ethyl][2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine

Product 1

HCID 23087457HCID 23087457, compoundYield 104.8%

Procedure

Synthesized from [2-(4-benzyloxyphenyl)ethyl][2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine according to an analogous synthetic method to Example 36, [2-(4-benzyloxyphenyl)ethyl]ethyl[2-(6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)phenyl]amine (976 mg) was used according to an analogous synthetic method to Example 22 to provide the title compound (835 mg).

Sources & evidence

ORD record
ord-c5c06c14afc74000a75771eb9a011d4e
Source dataset
uspto-grants-2011_06
Patent number
US07960412B2

Reaction notes

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