HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20550409, compound → 6-{2-{Ethyl {4-[2-(1,2,2,6,6-pentamethylpiperidin-4-ylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20550409 | HCID 20550409 | — |
| Reactant | Pivalic acid 6-{2-[ethyl(4-hydroxybenzoyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester | HCID 57934562 | — |
| Product | 6-{2-{Ethyl {4-[2-(1,2,2,6,6-pentamethylpiperidin-4-ylamino)ethoxy]benzyl}amino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-ol | HCID 57933872 | 14% |
Reaction Steps
Synthesized from pivalic acid 6-{2-[ethyl(4-hydroxybenzoyl)amino]-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (25 mg) and 2-chloro-N-(1,2,2,6,6-pentamethylpiperidin-4-yl)acetamide (23 mg) according to an analogous synthetic method to Example 567 and purified by LC-MS, the title compound (4.2 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07960412B2 |
| Source dataset | uspto-grants-2011_06 |
| ORD ID | ord-fa1f0c9da79443d8af286f4ae11b80b6 |
| Source note | uspto-grants-2011_06 |