HCID 11209223, compound → HCID 11358127, compound

HRID 2424181Notes

Reaction equation

HRID 2424181 reaction equation
C[O:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[CH:6]=[CH:5][C:4]=1[C:11](=O)[C:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)([CH3:14])[CH3:13].OC1C=C(OC)C=CC=1C(=O)C(C1C=CC(OC)=CC=1)(C)C>>[CH3:10][O:9][C:7]1[CH:6]=[CH:5][C:4]([CH2:11][C:12]([C:15]2[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=2)([CH3:14])[CH3:13])=[C:3]([OH:2])[CH:8]=1

Participants

3

Reactant 2

HCID 11209223HCID 11209223, compoundHCID 11771029HCID 11771029, compound

Product 1

HCID 11358127HCID 11358127, compound

Procedure

Synthesized from 1-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)-2-methylpropan-1-one according to an analogous synthetic method to Preparation Example 192 described below, 1-(2-hydroxy-4-methoxyphenyl)-2-(4-methoxyphenyl)-2-methylpropan-1-one (2.9 g) was used according to an analogous synthetic method to Preparation Example 185 described below to provide the title compound (1.9 g).

Workup

  1. customwas used according to an analogous synthetic method to Preparation Example 185

Sources & evidence

ORD record
ord-0c3aec7bbd5a4caa95c05e41a0208c3e
Source dataset
uspto-grants-2011_06
Patent number
US07960412B2

Reaction notes

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