HRID2424344

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID219989

3,5-DICHLORO-2-PYRIDINECARBOXYLIC ACID

C6H3Cl2NO2

结构：CC(C)(C)OC(=O)NC1=N[C@](C)(c2cc(N)ccc2F)CCO1

HCID67234727

未命名化合物

PRODUCTS

生成物

结构：C[C@@]1(c2cc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)CCOC(N)=N1

HCID53241150

未命名化合物

PROCEDURE

实验过程

The coupling of [(S)-4-(5-amino-2-fluoro-phenyl)-4-methyl-5,6-dihydro-4H-[1,3]oxazin-2-yl]-carbamic acid tert-butyl ester from experiment F1 (R3=Me) and 3,5-dichloro-pyridine-2-carboxylic acid followed by deprotection using procedure H yielded the title compound.