2,4-Dichloro-5-nitropyrimidine → HCID 58748430, compound

Participants

Reaction Conditions

Reaction Steps

2,4-Dichloro-5-nitro-pyrimidine (1.94 g, 10 mmol) and 2-amino-N -methyl-benzenesulfonamide (1.86 g, 10 mmol) are dissolved in CHCl3 (30 mL). The reaction mixture is heated at 61° C. for 2 h. The solvent is evaporated and the residue is washed with ether to give the title product. Rf=0.5 (n-hexane:ethyl acetate=1:1). 1H-NMR (400 MHz, CDCl3), δ (ppm): 2.67 (d, 3H), 4.6-4.7 (m, 2H), 7.41 (t 1H), 7.7 (t, 1H), 8.04 (d, 1H), 8.15 (d, 1H), 9.21 (s, 1H), 11.2 (s, 1H).

Provenance & Evidence